The Vaccine is a Rare Medicine in Unturned 3.
- The Vaccine has the same model as other syringes, only having a different color.
- The way in which the Vaccine is used in-game is very inaccurate compared to how a vaccine is used in real-life. In real life, a vaccine is taken before a disease is contracted in order to protect against it, not taken after the fact to reduce the severity of an infection.
- It is unknown how the player can craft their own Vaccine using a Can, Bricks, Glue, and Chemicals. Vaccines are usually created in sterile laboratories with precise equipment.